Description
| SKU # | E-AB-16442 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SPAST |
| Abbre | SPAST |
| Synonyms | ADPSP,FSP 2,FSP2,KIAA1083,SPG 4,SPG4,SPG4 gene,Spast,Spastic paraplegia 4,spastic paraplegia 4 (autosomal dominant,spastin,spastin) |
| Swissprot | Q9UBP0 |
| Cellular Localization | Cytoplasm, Cytoskeleton, Endoplasmic reticulum, Endosome, Membrane, Microtubule, Nucleus. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family.Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis.The encoded ATPase may be involved in the assembly or function of nuclear protein complexes.Two transcript variants encoding distinct isoforms have been identified for this gene.Other alternative splice variants have been described but their full length sequences have not been determined.Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
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